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Ted
Cruz has announced he is ending his campaign for the US Republican
presidential nomination, after losing heavily to Donald Trump in the
Indiana primary.
Earlier, Mr Cruz called Mr Trump a "liar" who was unfit to be president.
In the Democratic battle, Bernie Sanders is projected to beat Hillary Clinton in Indiana.
He trails Mrs Clinton in the all-important delegate count but after this victory he said the contest was still alive.
Live updates - reaction as Cruz drops out
Indiana results as they come in
Mr Cruz's advisers had targeted Indiana as the Texas senator's best hope of halting Mr Trump's march to the nomination.
"We gave it everything we've got, but the voters chose another path," he told supporters in Indiana, moments after the result was swiftly projected by the US networks.
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Cruz party over - Anthony Zurcher, BBC News, Indianapolis
Turn out the lights, the party's over. Ted Cruz and the #NeverTrump movement threw everything they had at Donald Trump in Indiana, and it wasn't enough. It wasn't even close to enough.They outspent him by more than a million dollars. Mr Cruz practically took up residence in the state for the past two weeks. He named Carly Fiorina as his running mate. Nothing worked.
If there was a defining moment of the Indiana campaign, it was Mr Cruz's fruitless attempt to reason with a group of pro-Trump supporters on Sunday.
Every argument he advanced was rebuffed. Every bit of evidence of Trump malfeasance was denied. Mr Cruz was shouting in the wind.
In the coming days there will be a great reckoning, as the party comes to terms with the prospect of Mr Trump as their standard bearer in the autumn. Some will make peace. Some will despair. Others will say "I'm with her" and reluctantly move to Hillary Clinton's side.
It will be an unprecedented spectacle in modern US political history.
The verbal attacks between him and Mr Trump had reached a new intensity on Tuesday.
Mr Cruz attacked the billionaire businessman as "totally amoral", "a pathological liar" and "a serial philanderer".
Mr Trump responded by calling Ted Cruz is a "desperate candidate trying to save his failing campaign".
But hours later, after Mr Cruz announced he was quitting the race, Mr Trump praised him as a "tough, smart competitor".
It
is looking increasingly like he will have to fight Mrs Clinton in the
autumn to succeed President Barack Obama, who steps down after two
terms.
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